Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-13 is a 169 amino acid cytoplasmic protein belonging to the acetyltransferase family and GNAT subfamily. Existing as two alternatively spliced isoforms, NAT-13 interacts with NARG1 and ARD1 as a possible catalytic component of the ARD1-NARG1 complex. NAT-13 is also known to interact with MAK10 and is encoded by a gene that maps to human chromosome 3q13.2.