Human Flt3 Ligand is a 24-30kDa glycoprotein with a 158 amino acid. Flt3 Ligand is expressed by T cells, bone marrow and thymic fibroblasts. The predominant biologically active form is membranebound isoform, which can be proteolytically cleaved to generate a biologically active soluble isoform. Flt3 Ligand synergizes well with a number of other colony stimulating factors and interleukins to regulate proliferation of early hematopoietic cells by activating Flt3.

This recombinant human FLT3 Ligand is produced by human cells. (Tag free)

Biological activity:
The activity was measured by its ability to stimulate the proliferation of the human acute myeloid leukemia cell line OCI-AML5.

Reconstitution:
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.