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2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed RNA synthesis, with IC50 values of 0.3 μM and 1.9 μM, respectively.2'-C-Methyladenosine also inhibits LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis. C-Methyladenosine also inhibited LRV1 in Leishmania guyanensis (Lgy) and Leishmania braziliensis.