图文详情
Application:WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF
Reactivity: Human,Mouse,Rat
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.