图文详情
Application:WB,IHC-P,IHC-F,IF,ICC/IF
Reactivity: Human,Mouse,Rat
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.