图文详情
Application:WB,IHC-P,IHC-F,IF,ICC/IF,IP
Reactivity: Human
Required for both DNA replication and mitosis.DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC).