图文详情
Application:WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF
Reactivity: Human
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.