图文详情
Application:WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF
Reactivity: Human,Mouse,Rat
DNA repair protein involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination.Plays a key role in NHEJ by promoting the ligation of various mismatched and non-cohesive ends.Together with PAXX, collaborates with DNA polymerase lambda (POLL) to promote joining of non-cohesive DNA ends.