图文详情
Application:WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF
Reactivity: Human,Mouse,Rat
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation.