图文详情
Application:WB,IHC-P,IHC-F,IF
Reactivity: Human
TIMP3 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP1, MMP2, MMP3, MMP7, MMP9, MMP13, MMP14 and MMP15.