图文详情
Application:WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF,IP
Reactivity: Human,Mouse
Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.