Application:WB,IHC-P,IHC-F,IF
Reactivity: Human,Mouse (predicted: Rat,Rabbit,Dog,Horse)
GCKR is a subfamily member of the SIS (Sugar ISomerase) family of proteins. It is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young.