图文详情
Application:IHC-P,IHC-F,IF
Reactivity: Human (predicted: Mouse,Rat,Pig,Cow,Dog,Horse)
High Mobility Group Box-1 (HMGB1) is a cytokine implicated in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. The cholinergic anti-inflammatory pathway, a vagus nerve dependent mechanism, inhibits HMGB1 release in experimental disease models