图文详情
Application:IHC-P,IHC-F,IF,Flow-Cyt
Reactivity: Human,Rat (predicted: Mouse,Rabbit,Pig,Cow,Chicken,Dog,Horse)
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]